Sentence examples for important endpoint to from inspiring English sources

One important endpoint to be measured in future studies is MRD negativity in standard or high-risk disease, since it is a significant predictor of PFS, OS, and potential cure in a fraction of patients109.

Clinical studies have increasingly incorporated HRQoL as an important endpoint to understanding patient care experiences.

The trough forced expiratory volume in 1 s (FEV1), measured 24 h after dosing, is an important endpoint to assess once-daily LABA efficacy [ 16].

In the sense of the presented test strategy, most important endpoints to be considered include further (a) biotic transformation/degradation, mobility and transport in porous media, and sorption to soil, sediment and sludge of the pristine and aged ENM.

As IPF is a progressive disease with no cure, HRQL and other patient-centered outcomes are important endpoints to evaluate in research and clinical practice [ 6].

Conservative estimates of treatment effect size should be adopted when planning larger phase II studies to confirm efficacy for clinically important endpoints, to better determine treatment effects, to support the biological rationale underpinning the intervention, to support safety data, and to better inform sample size calculations, feasibility and design for subsequent phase III trials.

In this article we also discuss our strategy of statistically correlating individual gene expression with biologically important endpoints designed to address the problem of evaluating functional relevance.

This important endpoint is more problematic to assess than other endpoints [2].

If disease control becomes an important endpoint, then trials have to be designed where strategies including reduced treatment intensity may reach this goal in a defined population of group-3 patients.

The most important endpoint of this study was to define whether CNB is an appropriate strategy for the diagnosis of lymphoma arising in a patient population from a primary care institution.

Health-Related Quality of Life (HRQoL) is an important endpoint in oncology clinical trials aiming to investigate the clinical benefit of new therapeutic strategies for the patient.