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An important element in assessing the clinical importance of QTc prolongation is the extent of change from baseline: an increase in QTc interval from baseline of >60 msec could be clinically significant and this is the recognised threshold for drug-induced arrhythmias in non-cardiovascular indications (ICH E14 guideline).
Estimating groundwater recharge to the aquifer system is a very important element in assessing the water resources in regions of the world with poorly developed hydrological measurement stations such as the West Bank.
An important element in assessing exposure is the biological matrix used for sampling.
By including a laboratory research component as well, the centers elucidate biologic mechanisms, an important element in assessing plausibility, and develop tools for screening and testing chemicals for possible regulation.
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Workplace-based assessments (WBAs) have emerged as an important element in this development, aiming to assess on the highest level of Miller's pyramid, the 'does' level [ 4, 5].
An important element in understanding a network meta-analysis is assessing the network geometry.
'Nudity is an important element in Hair.
The play becomes an important element in my composition.
Refusal is an important element in Munro's fiction.
Bus conductors are a very important element in Lagos Soundscapes.
Another important element in this system is internal auditing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com