Sentence examples for important drawbacks is from inspiring English sources

One of their most important drawbacks is the lack of standardisation as no quality controls like the ones daily used routinely in clinical chemistry laboratories do exist (Eisenstein, 2006).

One of the most important drawbacks is that both descriptive and mechanistic toxicology are labor and resource intensive and are too inefficient to comprehensively evaluate more than a fraction of the chemicals in commerce and the environment (Andersen and Krewski 2009).

Important drawbacks are the high cost, the need for sophisticated laboratory equipment and well-trained laboratory technicians.

However, as important drawbacks are the fact that only renders mean telomere length values per sample and does not allow the quantification of short telomeres.

The two-step approach provided some evidence of useful genetic variability on the residual variance of GBW and YW, but important drawbacks were identified.

However, an important drawback is associated to its acrylic polymeric character.

Another important drawback is that l1-SVD depends on a user-defined parameter which is not trivial to select.

This important drawback is carefully illustrated in Figure4, where the latency of a routing node is shown for the set of values WO = 4, AO = 3, SI = 30, and SR = 3.

One important drawback is that usually the needed closure models for the interphase forces, turbulence and coalescence and break-up are selected case-by-case, which hinder improvement of the predictive value.

Another important drawback is that recovery in clinical settings is not evaluated with a gold-standard GFR measurement (e.g., insulin clearance) but with the only GFR parameters that are clinically available, i.e., either SCr or the derived eGFR that are compared with their baseline.

Another important drawback is that they are only partly applicable to networks containing loops.