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Finally, we have shown that (i) the desorption energy required with MEA based DESs is much lower compared to the classical MEA process and that (ii) the energy required for compression remains the most important drawback for a such process, especially at low CO2 concentrations.
However, the most important drawback for practical applications is their complication, and chromatographic techniques do not lend themselves to rapid analysis or to on-site studies.
This is similar to other studies, which reported lack of time as important drawback for physicians [ 48- 50].
This constitutes an important drawback for economic evaluations in the context of public health and health promotion.
Frequent generation of influenza virus mutations is an important drawback for disease control, as reflected in the isolation of vaccine-escape viral mutants and in the antigenic variation of viral populations [ 19].
3– 6 Around one-half of patients with melioidosis have positive blood cultures, 7 and an important drawback for all antigen assays is that the median B. pseudomallei count in blood is 1 cfu/mL, 8 which is far below the achievable level of detection by the IFA.
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The high synthesis cost, the poor hydrothermal stability of the pore structure and the extensive leaching of the active metal sites in liquid phase heterogeneous catalysis are three of the most important drawbacks for the industrial use of the newly developed mesoporous crystalline materials (MCM-41, MCM-48, HMS, FSM, …).
Current criteria for assessing the severity of CAP, such as the pneumonia severity index (PSI) and the CAP severity on presentation to hospital scale (CURB65) are well validated, but have important drawbacks for routine care [ 3- 6].
In summary, under-estimation of short telomeres together with the fact that TRF cannot measure telomeres in individual cells, are important drawbacks for the use of TRF in aging and longevity studies.
Slow diffusion and, to a lesser extent, unidirectional transport are not able to accompany such a dynamic tissue growth, which is again an important drawback of these mechanisms for plant organ development, i.e. for systems that grow so rapidly and become so large.
However, it should be noted that an important drawback of phase partitioning separation methods for industrial uses is the slow rate of phase demixing.
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