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While appreciating the new contribution of the paper, we highlight an important difficulty with their method and suggest that data envelopment analysis (DEA) could be advantageously used to improve the multi-criterion evaluation.
An important difficulty with measuring enhancing brain tumors on MRI is that there is no quantitative cutoff for tissue enhancement on MRI.
An important difficulty with the use of such complex vaccines is the fact that relevant antigens are often obscure and thus in vitro immune monitoring may prove difficult.
Students maintained that the most important difficulty with living with the elderly is intergenerational conflict (30.3%), while an almost equal portion of the students (30.6%) expressed that there are no difficulties at all from living with the elderly.
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Nevertheless, from the existing evaluations, PAPPs studies [ 8, 9] and other national [ 10- 13]and international [ 14- 16] studies it is clear that there are important difficulties with respect to the correct implementation of preventive services and health promotion interventions and there is a high variability in their implementation.
The FIHOA consists of 10 items with a four-point Likert scale: "possible without difficulty" (0), "possible with slight difficulty" (1), "possible with important difficulty" (2) and "impossible" (3).
Two important difficulties in treating cancers with chemotherapy are drug resistance and toxicity.
Mental health problems among adolescents are prevalent and are associated with important difficulties for a normal development during this period and later in life.
Typical hydrodesulfurization and hydrodenitrogenation technology deals with important difficulties such as high pressure and temperature operating condition, failure to treat some recalcitrant compounds and limitations to meet the stringent environmental regulations.
We should stress that there are important difficulties to compare the current results with those reported by other authors due to the different in vitro susceptibility tests used and the potential variation of susceptibilities among the isolates and strains studied.
And important difficulties remain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com