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Both treatments were effective for the primary outcome of interest as the minimally clinically important difference for change in CDAI is 4.3.
The minimal clinical important difference for change in the mean ODI score is considered to be in the range of 8 10 points.
Statistical analyses were performed with SPSS 18.0 and Software R. 23 The minimal clinically important difference for change in the mean Oswestry disability index score is considered to be in the range of 8-10 points.
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A minimal clinically important difference for changes of physical activity is not yet available for patients with COPD.
The minimum clinically important difference for changes for patient-rated acute pain on this VAS scale is between 9 and 13 mm [ 17- 19].
Based on our previous research [ 59], our statistical calculations indicated that this study required 26 participants (with 80% power at 5% level of significance) to adequately detect a minimally clinically important difference for the following physical measures: change in Tibialis Anterior PPT, change in CPT, or change in NFR threshold.
The GRC was used to assess the minimum clinically important difference (MCID) for change in the short form knee function scale.
Further research investigating responsiveness to change over time and minimal important difference for the EAPIQ is warranted.
Pavy and colleagues [ 38] suggested a BASFI change of 17.5% is the minimum clinically important difference for AS patients.
The observed differences in mean PGWB total scores are clinically meaningful, since differences or changes of 4 to 5 points represent the minimally important difference for the PGWB [ 22, 26].
A change of 14 points has previously been reported to be the minimal clinically important difference for the AKPS.
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