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A number of studies have demonstrated that PARP1, PARP2, and poly(ADP-ribosyl)ation are important determinants for development [7], [51], [52].
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Prior studies illustrated that the location of APOE mutations is an important determinants for the development of LPG.
Clearly, other factors like natural fluctuations in prevalence of clones (18), patient compliance with antimicrobial drug regimens, fitness costs of drug resistance, or even tetracycline consumption (tetracycline and macrolide-resistance genes cosegregate) (19) might be important determinants for the development and spread of macrolide-resistant S. pyogenes.
Mode of development, phylogeny and shared ecology are the most important determinants for the evolution of an organism's specificity.
Pharmacokinetic properties are important determinants for the research and development (R&D) of the therapeutic agents, including the absorption and elimination characteristics, and poor pharmacokinetics will limit the development of drugs for clinical applications.
While antimicrobial resistance remains an important determinant for drug development and therapeutic choice, pharmacokinetic and pharmacodynamic parameters are having an ever‐increasing importance in defining performance targets for new and established agents.
In working populations, AHR is an important determinant for the development of symptoms[ 3].
Chronically elevated BP is an important determinant for the development and progression of atherosclerosis, the underlying pathology for most cardiovascular events.
International studies have also identified other important determinants for income inequality.
Pond size, habitat heterogeneity, elevation and dissolved oxygen were important determinants for species richness and diversity.
Technological advancement is known as the most important determinant for continuous economic development.
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CEO of Professional Science Editing for Scientists @ prosciediting.com