Sentence examples for important conformational changes from inspiring English sources
Our models may capture important conformational changes of CB1 receptor to help improve accuracy in future CB1 drug screening.
Under these conditions, lipase catalysis may be associated to important conformational changes that can be strongly modulated via biocatalyst and biotransformation engineering.
Circular dichroism (CD) spectra reveal that DNA undergoes important conformational changes upon adsorption onto the core-shell surface, which are reverted upon TMPyP encapsulation.
The KIAβW-ATP complex was determined using NMR spectroscopy and reveals the adenine ring sandwiched between the two Trp indole rings and that ATP binding induces important conformational changes in His1, Trp2, Lys4, Trp9 and Lys11 in the β-hairpin.
This residue is positioned between the proposed proton half-channel to the periplasm and the horizontal connection through subunit N, and is also near the essential Glu 144 of subunit M. The results suggest important conformational changes in this region for the delivery of protons to the periplasm, or for coupling the actions of subunit N to subunit M.
Altogether, the prediction analysis of HCV RNA revealed important conformational changes for patients with high anti-core+1/ARFP antibody responses within the core-coding region stem-loop structure that contains the core+1/ARFP initiator AUG-85 codon.
However, it did not tell whether the drop was related to the biologically important conformational change of integrin, that is, the conformational change from the bent to the extended form.
It seems likely, although no evidence is provided here, that Ni II) also does not induce the cis trans isomerization of Pro32, which is thought to be another important conformational change allowing dimer assembly.
This interaction involves S-phase-specific phosphorylation of BRIP1 at Thr 1133 and the TopBP1 BRCT repeats 7 and 8, which undergo important conformational change upon binding with BRIP1 (Leung et al. 2011).
The large and functionally-important conformational change seen in MutS with MutL and nucleotide binding fills a big gap in our understanding with likely broad impacts as noted below.
