Sentence examples for important conformational change from inspiring English sources
The deuterium incorporation profile along the sequence allows the identification of the regions that exhibit the most important conformational change.
This interaction involves S-phase-specific phosphorylation of BRIP1 at Thr 1133 and the TopBP1 BRCT repeats 7 and 8, which undergo important conformational change upon binding with BRIP1 (Leung et al. 2011).
However, it did not tell whether the drop was related to the biologically important conformational change of integrin, that is, the conformational change from the bent to the extended form.
It seems likely, although no evidence is provided here, that Ni II) also does not induce the cis trans isomerization of Pro32, which is thought to be another important conformational change allowing dimer assembly.
The Gaudet lab uses a combination of structure determination and biochemistry to understand how TAP undergoes important conformational changes during a catalytic cycle.
A careful analysis of isolated wild type and mutant PFN1 trajectories revealed two important conformational changes, with potentially significant consequences, observed in only one of the wild type simulations (Fig. 6).
Under these conditions, lipase catalysis may be associated to important conformational changes that can be strongly modulated via biocatalyst and biotransformation engineering.
Circular dichroism (CD) spectra reveal that DNA undergoes important conformational changes upon adsorption onto the core-shell surface, which are reverted upon TMPyP encapsulation.
The KIAβW-ATP complex was determined using NMR spectroscopy and reveals the adenine ring sandwiched between the two Trp indole rings and that ATP binding induces important conformational changes in His1, Trp2, Lys4, Trp9 and Lys11 in the β-hairpin.
This residue is positioned between the proposed proton half-channel to the periplasm and the horizontal connection through subunit N, and is also near the essential Glu 144 of subunit M. The results suggest important conformational changes in this region for the delivery of protons to the periplasm, or for coupling the actions of subunit N to subunit M.
