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Cyclin E, CDK2, and CDK4 are important complexes responsible for the progression of cells through the G1 phase of cell cycle and initiation of DNA replication [55].
Possible explanations may include binding outside the catalytic pocket of YscN and affecting assembly of biologically important complexes or targeting sterically similar sites in other bacterial proteins important for regulating the effector secretion [38], [39], [40], [41].
Accordingly, it contains a relatively small number of complexes (506) and lacks many other important complexes.
These predictions should contribute to the determination of the structures of these biologically important complexes.
The GO category "cellular component organization and biogenesis" contained important complexes such as signal recognition particle, coatomer protein complex and the splicosome.
The complex page provides information on important complexes in epigenetics, including proteins involved in complex formation, the molecular and specific targets and products, as well as relevant PMID references supporting the information.
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