The present study may have important clinical implication.
One important clinical implication of CSCs is their role in cancer metastases, as reflected by their ability to initiate and drive micro and macro-metastases.
As a conclusion, our study has a potentially important clinical implication, suggesting that bio-ADM measurement could be added to CS evaluation because of its prognostic value after the initial phase of management in patients with CS.
Conversely, our study has another important clinical implication.
An important clinical implication of ER status is the benefit patients derive from endocrine therapies such as tamoxifen.
An important clinical implication from our results is that we establish TP53 pathway as an attractive therapeutic target in ALL.
Our results provide new insight into the molecular processes underlying the development of carboplatin resistance in ovarian cancer and have important clinical implication.
An important clinical implication of this may be that the COMTval158met related differences may be more expressed in individuals where the inhibitory system is already challenged and sensitive, e.g. chronic pain patients.
