Sentence examples for important checkpoint in from inspiring English sources

In mammalian cells, G1/S transition is an important checkpoint in the cell cycle.

Finally, Gi-mediated inhibition constitutes an important checkpoint in determining nociceptor excitability.

Thus the balance between α- and β-secretase activities may be an important checkpoint in the control of skeletal muscle metabolism.

The results suggest that smoking represent an important cause of systemic inflammation, pointing out the Th17/Treg balance as an important checkpoint in the pathophysiology of lung adenocarcinoma.

Meiotic crossingover is an important checkpoint in almost all sexually reproducing eukaryotic organisms and is mediated by the Synaptonemal Complex (SC) during meiosis I.

Moreover, the strong interaction of several misfolding AGT mutants with molecular chaperones suggests that these chaperones might be important checkpoints in AGT folding and misfolding [ 34, 50, 57].

These genes are known to be important checkpoints in flavonoid biosynthesis as shown by microarray experiments performed under various abiotic stress conditions [ 7].

Consequently these key proteins and/or enzymes constitute important checkpoints in the endogenous and exogenous glucose homeostasis; hence can be exploited in the mechanistic study of both conventional and potential anti-diabetic drugs.

Primary practices and specialized clinics are important checkpoints in this process [ 26], although population strategies are needed to favor a smoke-free environment and an appropriate atmosphere for sustained quitting.

Mec1p, the most important checkpoint kinase in yeast, has a minor role in telomere length regulation (Ritchie et al. 1999).

Polo-like kinase-1 (PLK1) is a crucial driver of cell cycle progression and its down-regulation plays an important checkpoint role in response to DNA damage.