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Reproductive isolation (RI) is widely accepted as an important "check point" in the diversification process, since it defines irreversible evolutionary trajectories.
In particular, this study has shown that an important check point of selection during B-cell transition was impaired at high dosages of this estrogen.
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If the phosphoryl moiety has no obvious effect on the recognition of peptide 131 151 by HSC70, it apparently represents an important check-point in the P140 pathway for γδ T cell recognition.
The most important system in any Check Point FireWall-1 configuration is the management server, renamed SmartCenter Server in FP3.
For eukaryotic organisms, cell size is an important control at check points for cell division [ 26, 27].
Furthermore, changes in protein levels of several important cell check-point and apoptosis regulators were examined, including p53, Chk1, Chk2, Cdc25C and p21.
While CPT1 is recognized to be an important regulatory check-point in controlling the rate of fatty acid β-oxidation, increases in CPT1 protein levels may not be sufficient to enhance enzyme activity, given the known allosteric inhibition of CPT1 by malonyl CoA.
Ska2 participates in mitotic spindle formation and function during metaphase; it is also important for monitoring aberrant kinetochore assembly during the spindle check point step of mitosis [ 33].
The success of immune check point therapy demonstrates that elimination of the inhibitory pathways that block effective antitumor T cell responses is important in cancer therapy.
Check Point has launched "smart" clients.
Check Point repelled them all.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com