Sentence examples for important challenge however from inspiring English sources

How Mr Donaldson responds will be watched closely, given the experience of Mr Pitt, who lost his chairmanship in big part because of his support for Mr Webster, a consummate Washington insider but with little experience in finance.Mr Donaldson's most important challenge, however, will be to supply the vision for how America's markets are to be transparent and open enough to attract investment.

The most important challenge, however, is to understand and target the mechanisms that counteract the proapoptotic signals upon loss of E-cadherin in LCIS and ILC.

The development of strategies for designing effective linkers remains an important challenge, however, because of the large affinity enhancements that are possible with bivalent ligands in optimal cases.

An equally important challenge, however, can be found in the question as to "whether the analyte will find the nanometer-sized surface".

It faces important challenges, however, including: (1) high commodity cost; (2) often-strong provider resistance to IUDs and difficult programmatic requirements; (3) need for demand creation, including assessing if markedly reduced menstrual bleeding is attractive to clients; and (4) the many requirements for introducing any new contraceptive.

However, one very important challenge still remained: How could Internet users locate the rich resources potentially available to them?

However, important challenges also still remain.

An important challenge for these applications, however, is the incomplete and noisy nature of PPI data.

However, an important challenge in using whole genome sequencing will be the interpretation of the data.

However, an important challenge for these applications is the incomplete and noisy nature of the PPI data [ 15].

However, an important challenge is to ensure the availability of analysis tools to the entire community of microscope users.