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Thus, UPR is an important cellular response for the mass production of functional secretory proteins from unfolded proteins in cells which produce them in large amounts.
Autophagy is an important cellular response to numerous diseases.
The energy metabolism shift is an important cellular response to hypoxia.
Autophagy is an important cellular response to stress like toxins and oxidative stress.
The adhesion of circulating leukocytes to the endothelium is an important cellular response to inflammation.
Activation of p53 is an important cellular response to DNA damage.
Similar(50)
The physiological and pathophysiological roles of KATP channels have been studied primarily using KATP channel blockers and K+ channel openers, but there is no direct evidence on the role of the KATP channels in many important cellular responses.
Now Lin et al. explore if additional molecules released from the mitochondria might also initiate important cellular responses during the reoxygenation of oxygen-deprived tissue.
The TOR complex controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport, and autophagy, which are important cellular responses implicated in increased life span [ 4].
Its chronic administration to obese animals revealed important cellular responses of both liver and adipose tissues for controlling lipid biosynthesis and thermogenesis, as well as the induction of insulin resistance.
The activation of the nuclear factor κB (NF-κB) pathway as a possible anti-apoptotic route represents such an important cellular stress response.
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