Sentence examples for important cellular and from inspiring English sources

This review highlights the role of HDACs in diabetes mellitus and outlines several important cellular and molecular mechanisms by which HDACs regulate glucose homeostasis and can be targeted for the treatment of diabetic microvascular complications.

Here we review recent data showing that several widely used protease inhibitors, including indinavir, saquinavir, ritonavir, and nelfinavir, can affect important cellular and tissue processes such as angiogenesis, tumour growth and invasion, inflammation, antigen processing and presentation, cell survival, and tissue remodelling.

Because this circuit of lipoxin formation appears to be of physiological relevance in resolution, therapeutic modalities targeting this and related systems should allow for the development of novel therapeutic agents (i.e., agonists of the important cellular and physiological responses required for timely resolution).

However, high densities of expression of functional α7-containing nAChRs in CA1 pyramidal neurons may not be necessary for triggering important cellular and network functions, especially if activation of α7-containing nAChRs occurs in the presence of positive allosteric modulators such as PNU-120596.

Polycomb group (PcG) proteins are epigenetic gene regulators implicated in important cellular and developmental processes.

These data lend support to the notion that correcting acidosis represents more than 'treating numbers' and instead addresses important cellular and subcellular events.

O-GlcNAc is critical for many important cellular processes and has an extensive and dynamic interplay with phosphorylation.

The developing pollen from microspore to mature stages in rice and Arabidopsis shares important cellular events, and their mature pollen grains are tricellular [ 33].

Cluster thinning has a profound effect on several important cellular processes and metabolic pathways including carbohydrate metabolism and the synthesis and transport of secondary products.

Notably, integrated analysis showed enrichment of genetic lesions affecting several important cellular processes and pathways, including chromatin modification, ERBB-PI3K signaling and autophagy machinery.

Many of them have important cellular functions, and often functions are directly related to secondary and tertiary structure.