Sentence examples for important causative role from inspiring English sources

Issues of particulate debris, joint fluid lubrication, and even femoral component design and metallurgy may all play an important causative role.

Bruxism has an important causative role in the increased concentration of mercury in urine (Barregard et al. 1995).

Mitogen-activated protein kinase p38 plays an important causative role in senescent cells following telomere shortening [ 33- 35].

The most common oral cavity infectious disease in which an important causative role is played by biofilms formed by microorganisms on the teeth and gums surface is dental caries.

These results together suggest that zinc transporter ZIP6 may not only play an important causative role in cell migration, but also be a viable indicator of tumours that have the capability to spread.

This is a complex pathway responsive to stress stimuli and involved in cell differentiation and apoptosis and has been shown to have an important causative role in senescence [ 31].

PM2.5-induced endothelial dysfunction and elevated blood pressure (BP) may be playing important causative roles (Brook 2008).

Our findings might therefore shed new light on the important question whether delirium plays a causative role in the development of dementia in later life, or if delirium is the first sign of dementia.

In order to prove a causative role, it will be important to define the molecular mechanisms through which cadmium in low exposure can cause adverse health effects.

As D310 mutations occur at high frequency in pre-malignant lesions, it is important to consider whether they have a causative role in breast carcinogenesis.

While H4 lysine 5 acetylation clearly correlated with malignant phenotype of the breast cancer cell lines, it will be important to determine whether this modification plays a causative role.