Sentence examples for important birth defect from inspiring English sources

Important birth defect factors include heredity, environment (physical and psychological conditions, socioeconomic status, health etc).

Congenital heart defects (CHD) represent a high percentage of clinically significant birth defects, occurring in ∼8 per 1,000 live births and being the most common malformation and an important public health burden.

NC-related anomalies comprise up to 20% of clinically important human birth defects (Bolande, 1974; Dolk et al., 2010), so it is important to ascertain whether PCP mutations are a likely cause.

The findings have implications for genital development in general, which is important because birth defects in the external genitalia are among the most common congenital defects in humans, said study researcher Martin Cohn, a developmental biologist at the Howard Hughes Medical Institute and the University of Florida.

This information is especially important for birth defects diagnoses that may present weeks or months after delivery.

The biology of neural crest regulation is also of significant biomedical relevance because neurocristopathies form an important class of birth defects (Bergstrom et al., 2005; Bolande, 1997; Inoue et al., 2007).

Results in death; Is immediately life-threatening; Requires hospitalisation or prolongation of existing hospitalisation; Results in persistent or significant disability or incapacity; Is a congenital abnormality or birth defect; Is an important medical condition.

An adverse event was reported as serious if it: was fatal or life threatening; required or prolonged hospitalisation; resulted in persistent or significant disability or incapacity; was a congenital anomaly or birth defect; was an important medical event.

Results in death Is life-threatening Requires hospitalisation or prolongation of existing inpatients´ hospitalisation Results in persistent or significant disability or incapacity Is a congenital anomaly or birth defect Any other important medical condition which, although not included in the above, may require medical or surgical intervention to prevent one of the outcomes listed.

A serious adverse event (SAE) is an AE that fulfils one or more of the following criteria: Results in death; Is immediately life-threatening; Requires hospitalisation or prolongation of existing hospitalisation; Results in persistent or significant disability or incapacity; Is a congenital abnormality or birth defect; Is an important medical condition.

21 There is also an important increase in birth defects and developmental disabilities due to maternal conditions.