Sentence examples for important binding partner from inspiring English sources
Also β-catenin, an important binding partner of E-cadherin, was processed.
This study was the first to uncover Bruton's tyrosine kinase (BTK) as an important binding partner of MyD88 L265P, and showed that the L265P mutant activates BTK in WM.
The co-repressor CoREST, together with HDAC1 and HDAC2, are important binding partners of LSD1 at some promoters.
Although the intermediate region between the WW and C2 domains is not so conserved, this region commonly contains potential coiled-coil sequences and has several important binding partners.
Aberrant DISC1 proteins putatively arising from the der 1 chromosome lack the final 257 amino acids, required for interaction with a number of important binding partners, including NDE1/NDEL1 (15).
Annexins are important binding partners of S100 proteins and they contain a short helical sequence feature at the N-terminus that allows binding to several members of the S100 family.
To ensure we had not missed any important binding partners, we also performed an E12488-651 library screen using a reduced-stringency method that is designed to favor the detection of lower-affinity interactions.
Knockdown of APPL1, an important intracellular binding partner for AdipoR, also significantly reduced the ability of adiponectin to prevent H/R-induced ROS generation and caspase 3 activity.
We identify Nup153 as an important impβ binding partner at the nuclear face of the pore.
Future studies will have to identify additional residues outside the PIR1 P-loop that take part in β-phosphate stabilization and facilitate its hydrolysis as well as address how the PIR1 noncatalytic C-terminal extension (residues 206 330) affects enzymatic activity, likely by regulating association with RNA and other important physiological binding partners.
4) It was confusing as to why a construct missing both MyTH4 and FERM were needed to "not rescue" the phenotype - i.e. lacking the ability to bind to one or the other binding partner of an important bridging protein should both give the "not rescue" answer, no?
