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These initial changes may represent important alterations of physiological pathways that culminate in altered protein turnover and/or recruitment of satellite cells to support muscle growth.
This work provides a tool to translate environmental changes such as global climate change and human intervention into changes in dispersal behavior, which in turn may lead to important alterations of biodiversity and biological invasion patterns.
Thereby, important alterations of the brain monoaminergic systems have been involved in mood disorders [14], [15].
The lack of GPR3 could possibly impact on the activity of the efferent connections of the habenular complex and account for the important alterations of the brain monoamines that we found in various brain areas of mutant mice.
Here we could demonstrate important alterations of the tissue-dependent microvascular capacity in patients after successful resuscitation.
In summary, we observed important alterations of metabolism (increase in body weight, waist and hip circumferences, LDL, triglyceride, and total cholesterol serum levels) in our patients receiving adjuvant therapy.
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In the present study, important alterations on the ultrastructure of L. infantum promastigotes were also observed on B2-treated parasites.
Therefore, it is imperative for the radiologist to understand that although current imaging protocols are not designed specifically to evaluate the venous system, venous injuries may nevertheless be identified, with the potential for important alteration of management [68].
In contrast, MDMA-treated animals housed at 26°C showed an important alteration of striatum structure and a significant decrease of TH levels.
One of the major pathophysiological issue in explaining this phenomenon is the important alteration of autonomic cardiovascular control observed in sleep disorders.
On the contrary, the strong hyperthermia induced by MDMA at 26°C caused severe neuronal damage that triggered a marked glial activation, an important alteration of the striatum structure, and a significant reduction of TH levels.
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