Sentence examples for important affinity for from inspiring English sources

In this work, two derivatives containing an amide or an ester functional group with different lipophilicity, were selected for their important affinity for sigma-1 receptors.

Recently, it was shown that the pyruvate:ferredoxin oxidoreductase (PFR) enzyme of Chlamydomonas possesses an important affinity for oxaloacetate [ 53], which opens up the possibility that acetate, via the glyoxylate pathway, might also be coupled to fermentative H2 production (Fig.  6).

The scFv51 shows a high stability, a property often more important than affinity for the antigen in determining intracellular behaviour and efficacy, together with a high solubility.

The elements and tendencies common to the Chinese, Korean, and Japanese cultures are vast, but two kinds of visual expression are especially important: a strong affinity for the clay-formed vessel and calligraphic expression through the ink-charged brush.

This valuable information can then be used to identify which residues of the binding site are potentially important for affinity and selectivity.

A number of residues important for affinity were identified, and a triple mutant combining A1D, S61R, and G62R resulted in a KD of 460 pM for hen egg lysozyme, a 20-fold improvement over wild-type 5A7, and the highest KD yet reported for VNAR antigen interactions.

Human UNG2 is a multifunctional glycosylase that removes uracil near replication forks and in non-replicating DNA, and is important for affinity maturation of antibodies in B cells.

Furthermore, these sites affected by positive selection have been shown experimentally in other cystatins to be important for affinity with target proteases.

However, the many lipophilic interactions are also important for affinity, as is the interaction between the backbone-C=O of Asp381 and a fluorine atom in the trifluoromethyl group of AMN107 (Manley et al, 2005).

Perhaps most important, both had an affinity for Midcentury architect Gregory Ain.

Further refinement of this class of compounds on functional groups that are important determinants of their affinity for DYRK1A could lead to high affinity inhibitors of tau phosphorylation.