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Not the most important actor of course.
This oxidative product of 5-methylcytosine (5-mC) constitutes a new and important actor of epigenetic mechanisms.
Thereby, CFTR could be considered as an important actor of ELF antioxidant homeostasis and thus an intrinsic cause of oxidative imbalance in CF airways from human patients as well as Cftr knockout mice.
Although subfamily AA3_1 was considered an important actor of lignocellulolysis [ 66], we found no significant correlation with the nutritional modes.
Caffeic acid is reported to have antimetastatic and antitumour activity by suppressing MMP-9 enzyme, an important actor of metastasis and cancer onset [ 38].
Since a growing number of evidences indicate that autophagy seems to be an increasingly important actor of cardiomyocyte remodelling, we also studied its implication in MMV compared to healthy mitral valves (HMV).
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Atkins, the linchpin of the play, shows the mighty miniaturism that has made her one of the most important actors of the past 50 years.
Mitochondrial biogenesis and metabolism have recently emerged as important actors of stemness and differentiation.
Mesothelial cells are important actors of the peritoneal homeostasis; we determined their role in the acquisition of chemoresistance of ovarian tumours.
All together, these results show that two ARE-containing mRNAs, encoding important actors of male differentiation, exhibit a temporally regulated localization: initially concentrated within the CB of early round spermatids, they subsequently become associated with polysomes, concomitantly with HuR, at later stages of differentiation, as demonstrated for Brd2.
In addition, they are important actors of muscle repair as they activate differentiation of satellite cells, which in turn inhibit differentiation of FAPs into adipocytes under healthy conditions.
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