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With the h2i modules fixed in this position, the ATPase sites would be unable to adopt a productive hydrolysis conformation because each ATPase site is fundamentally tied to h2i position, potentially to prevent further ATPase activity during an important activation event.
In general, we noted an important activation of genes with proapoptotic activity, including BAB, BAX, NOXA and P21 (CIS and PTX + CIS), as well as in PTX groups for CASPASE-3 gene.
16N and 17N are determined to be the most important activation products in the coolant water in terms of their impact on ITER design and performance.
Modern PES play an important activation role.
We hypothesized that, if the initial signaling event is important, activation of Akt should reverse the phenotype of the ORF4 mutation.
The study suggests that the conserved OCT4/SOX2 synergistic action is an important activation mechanism in the FGF, LIF, NANOG and OCT4 directed pathways, which are furthermore regulated by a feedback loop formed by ESG1, FOXD3 and SOX2.
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Activation of Ca2+, K+, and Cl− channels is important for activation of T-cells in the early phase of an immune reaction [ 35, 41].
Are they storing factors important for activation?
Recently, dimerization was shown to be important for activation.
The protein stability mediated by ubiquitin E3 ligases is important for activation of DREB2A (Qin et al. 2011).
Several mechanisms are associated with brain dysfunction during sepsis; one of the most important are activation of microglia and astrocytes.
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