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In spite of MMP-2 classified as a self-antigen, the fact that cross-presentation is the only way to present this MMP-2 epitope underlines the importance to target this type of antigen in immunotherapy protocols.
This aspect underlines the importance to target these proteins to further improve existing anti-cancer therapies.
This example of ethnic inequity highlights the importance to target those most in need.
These different pain phenotypes in OA can be of importance to target pain treatment, but at present very little OA intervention research in this direction has been done.
All cohorts include subjects in mid-life, a time when early onset CVD manifests and where it is of importance to target improved risk estimation (Table 2).
A study focusing on a cash transfer scheme in India has shown the importance to target the poorest women when designing policies as well as addressing the quality of obstetrical care at the health facilities [ 27].
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Accepting the validity of these data, the PCR/ESI-MS test could be of importance to help target antimicrobial therapy in patients who have already started antimicrobials and have negative cultures (salvage microbiology) (29).
Maximum importance was given to target dose coverage.
The ability to delineate the control mechanisms of Chk1 is of critical importance in order to target Chk1 with the aim of increasing the selectivity and specificity of anticancer drug treatments.
13, 14 Although several treatment options exist for individual components of this cluster, an optimal approach aimed at correcting the metabolic derangement is of paramount importance in order to target residual CV risks.
This is, however, of potential importance as therapeutic interventions to target vascular remodelling could have an important role to play in both treatment of small AAA and prevention of plaque rupture and subsequent thrombotic events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com