This suggests that the magnitude of gene expression changes may be a poor predictor of their importance, supporting the notion that analyses biased towards large gene expression changes may miss important insights.
The primary importance of the notion of contempt is that it warrants judicial action in defense of the judicial or legislative power itself.
The set D of designated values is of central importance for the notion of a valuation system.
With respect to our present inquiry, what is of special importance is the notion of a religious belief: what does a belief have to be like to be religious?
This dimension has achieved importance through the notion of the "grammarian's dream" (Halliday 1961; Hasan 1987): the idea that grammar and lexis are not two distinct phenomena, but instead lexis should be seen as the most delicate grammar.
And it is widely held, not least by realists, that even many of our best scientific theories are likely false, strictly speaking, hence the importance of the notion that theories may be "close to" the truth (that is, approximately true) even though they are false.
Second, and of equal value and importance, is the notion of regularity within that change.
Of special importance is the notion of a closed linear subspace of a Hilbert space that, with the inner product induced by restriction, is also complete (being a closed set in a complete metric space) and therefore a Hilbert space in its own right.
This observation underlines the importance of the notion of the pro- and anti- inflammatory balance, especially for these two major cytokines, in the context of pregnancy and infection with pathogens [13], [46], [47].
