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According to this outstanding importance, single nucleotide polymorphisms or pathological mutations in one of the four human genes encoding GIRK subunit isoforms are causally related to various diseases, including primary aldosteronism and hypertension, alcohol abuse, atrial fibrillation, Andersen & Barter syndromes and congenital hyperinsulinism [6 10].
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Among such approaches, the importance of single individual haplotyping (SIH), which infers individual haplotypes from sequence fragments, has been increasing with the advent of novel sequencing techniques, such as dilution-based sequencing.
Our comparative analysis of CREB1 expression during aging in the intact ganglia and individual neurons highlight the importance of single neuron study of aging.
Given the importance of single bond events, each ISWBC BOND maps to a single ligand-ligand bond.
2 In multivariate PLS, it is of interest to "dissect" the importance of single attributes, with regard to individual responses.
In presence of multiple responses, it is of particular interest how to appropriately "dissect" the model, to reveal the importance of single attributes with regard to individual responses (for example, variable selection).
Despite the importance of single particle motion in biological systems, systematic inference approaches to analyze particle trajectories and evaluate competing motion models are lacking.
For example, the ability of oxygen to access and react with minerals in the rock matrix may be of paramount importance for single fracture conceptual models.
The mathematical function we obtained from the net seems useful in determining the relative importance of single variables related to survival.
The genome project has made biologists appreciate the importance of "single nucleotide polymorphism" (SNP)—minor variations in DNA that define differences among people, predispose a person to disease, and influence a patient's response to a drug.
Small labeling tags and free choice of which fluorophore to use and where to put it into the protein are of particular importance for single molecule science and superresolution microscopy.
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