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Remember the importance of the transcript.
Work to assess the functional significance of alternatively expressed Syt genes has barely begun [ 103, 107- 112] so it is difficult at present, to judge the importance of the transcript variants listed in this collection.
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Higher expression of CD36 in cells treated with DMIOA compared with non-treated cells in the present study suggests the importance of this transcript in the adipogenesis of hen fat cells.
The evidence presented in this study, for a potential modulating role of PCA3 in the AR signaling, highlights the importance of this transcript as a potential target for treatment.
To investigate the functional importance of the Paupar transcript we performed transcriptome profiling of Paupar knockdown in N2A cells.
Despite the importance of these transcripts, few studies have characterized marine crustacean lncRNAs or the modulation of these in response to chemical exposure.
McCarthy et al recently demonstrated the large differences in prediction of loss-of-function (LoF) variation when RefSeq and Ensembl transcripts are used for annotation, highlighting the importance of the reference transcripts on which variant functional annotation is based.
Comparative transcriptomics [ 12, 13] as well as computational studies [ 14, 15] showed that between one and two thirds of human lncRNAs are conserved among Eutheria, emphasizing the functional importance of these transcripts.
The results of our comparison of annotations obtained using REFSEQ and ENSEMBL transcript sets emphasise the importance of the choice of transcript set used for annotation.
Lücker et al. [ 63] also demonstrated the importance of VvValCS transcript in the production of terpenoid compounds during the late ripening stages of Gewürztraminer cultivar.
Given a set of k transcripts, we are interested in the importance of each transcript for explaining the total RNA-Seq data.
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