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Considering the importance of PAR, we hypothesized that the I/E model would also apply to PAR both as predictor and as outcome.
Evidence is accumulating for the importance of PAR regulation in the embryo.
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The importance of Par-4 as a therapeutic agent can be exploited by using appropriate Par-4 delivery systems, specifically into Par-4-deficient cells, thereby restoring chemo-sensitivity and preventing recurrence.
As a first step toward elucidating the relative importance of PAR-1 and Shaggy on tau toxicity and phosphorylation, we examined the effects produced by the misexpression of the wild-type and S2A tau transgenes alone.
Illustrating the potential importance of PAR-1 signaling in COPD, we have previously shown that PAR-1 knockout mice develop emphysema (3) but are protected from chronic bronchitis, supporting the notion that PAR-1 signaling pathways may influence clinical phenotype in this disease context.
"Yeah, absolutely," Woods said, acknowledging the importance of the par putt.
Some evolutionary considerations have similarly assigned angiogenesis an importance on par with barriers such as the abrogation of apoptosis (e.g., DeGregori 2011; Sprouffske et al. 2011).
However, the precise roles of PARs in gingival tissues and the importance of specific PARs in the pathogenesis of periodontitis remain to be elucidated.
The importance of IGF-1 signaling in PAR and MFP development has been discussed above and in previous papers/reviews (e.g., [ 4, 60]).
He says the importance of the referendum is on a par with the country's 1991 plebiscite on independence.
High predictor importance of sea surface temperature (sst), irradiance (par), mixed layer depth (mld), and carbon-based primary production model (cbpm) support the idea that the sedimentary bacterial biomass may be imported in the form of sinking particles [54], [56].
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