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Describe the importance of modification of glycemic targets in patients with diabetes, considering key clinical factors such as established comorbidities and hypoglycemia risk.
Early treatment of open bite during mixed dentition has been supported by many authors [35], as it represents the importance of modification of habits or reducing the need for orthognathic surgery after puberty.
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This is a further example for the importance of modifications at RNA-RNA interaction sites.
The importance of modifications in intron 1 for variation in expression of the Vrn genes was established through the analysis of allelic variants.
The number of features corresponding to transcription factors is much larger than the number of modifications and the importance of individual transcription factor is much smaller than importance of modifications.
Previous studies have also highlighted the importance of modifications to cell wall structure in the response to salinity [ 50, 51] and cell wall-related genes were strongly regulated by salt stress in tomato roots [ 27].
Besides the importance of PCNA modification in DDT, 9-1-1 modification in yeast seems to play a role in DNA damage management as well [27].
Dimethylation of these adenosines is one of most conserved rRNA modifications in nature (24, 41), and the importance of the modification for ribosome biogenesis has been demonstrated in bacteria (27, 38), yeast (20), plants (42, 43) and mammals (17– 17).
Genes and diet are important factors affecting the levels of UA; therefore, we emphasise the importance of lifestyle modification interventions for people with prehypertension.
Accumulated evidence in various organisms has pointed to the importance of epigenetic modification in the form of cytosine methylation as an important mechanism for repressive control of TEs activity (see Introduction).
The importance of dietary modification for disease prevention is widely accepted.
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