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(See also Becker 1998; Lormand 1996 and Margolis & Laurence 1998 for more accounts foregrounding the importance of instability, and Pagin 2006 for one of the few general expositions of the view that doesn't make this assumption).
A systematic and thorough investigation into the molecular mechanisms of low B.t. mRNA levels (and the consequential low levels of B.t. toxins) by Pamela Green and co-workers, led to their conclusion on the importance of "instability of mRNA as a cause of limited expression of foreign genes" in general [ 13].
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In view of the importance of instabilities that may occur at low-pressure and -flow conditions during the startup of natural circulation boiling water reactors, startup simulation experiments were performed in the Purdue University Multi-Dimensional Integral Test Assembly (PUMA) facility.
The importance of mechanical instability of the β phase in bringing about this transformation has been investigated.
The importance of gravitational instability in determining the emulsification of vitreal tamponades is discussed.
The importance of chromosomal instability for somatic cancer evolution was postulated by Nowell (Nowell, 1976).
The importance of chromosomal instability as an initiating event of cancer development has also been evaluated by different mathematical approaches which model evolutionary dynamics quantitatively (Michor, 2005; Nowak et al., 2004).
The biological importance of genetic instability and DNA repair mechanisms in cancer development is particularly well illustrated by the autosomal recessive disorders ataxia telangiectasia, Fanconi anaemia and Nijmegen breakage syndrome.
We further highlight the importance of Coulombic instabilities in developing polymeric structures.
Mutation of dinucleotides within exons is expected to directly affect protein sequence and potentially also function; of importance, instability of exonic dinucleotides within 14 cancer-associated genes was detected in tumors of head and neck squamous cell carcinoma patients (Wang et al. 2012).
Since taking office, Secretary of Defense Donald H. Rumsfeld has made clear he considers the Pacific to have rapidly growing military significance for several reasons: the rising power of China; the economic importance of South Korea, Japan, Hong Kong and Singapore; the instability of Indonesia; and the development of long-range ballistic missiles in North Korea.
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