Sentence examples for importance of identifying pathways from inspiring English sources
The speakers reinforced the importance of identifying pathways and networks that make biomarker candidates biologically meaningful and credible.
In view of the worldwide epidemic of obesity and associated metabolic disorders it is obviously of importance to identify pathways that can be manipulated genetically or pharmacologically and regulate the induction of UCP1 expression and recruitment of brown-like adipocytes in white adipose tissues.
It is therefore of high importance to identify pathways that can prevent or reverse protein aggregation.
This pathway-level analysis is hypothesis generating and will require further laboratory validation to determine the importance of the identified pathways (for example, immune response, endothelial-cell regulation, G-protein signaling) in the biology of chemotherapy response in ER-negative breast cancer.
A recent review highlighted the importance of identifying "core" fibrogenic pathways in multiple organs.
The continuous rise in obesity rates around the world underscores the importance of identifying the molecular pathways by which obesity contributes to the pathogenesis and progression of numerous chronic diseases, including breast cancer.
In addition, this stratification of the bioinformatic information was performed to make it possible to verify these findings using quantitative real-time PCR and to validate the biological importance of the identified pathway in further biological experiments.
Besides the importance of identifying pathognomonic mutations and pathways, sequencing is also a powerful tool to differentiate related entities.
The observation that steroid use may actually enhance alveolar epithelial damage by promoting apoptosis (Dorscheid et al., 2001) highlights the greater importance of identifying disequilibrium in particular molecular pathways over broadly classifying IPF as a purely inflammatory condition.
The importance of identifying new therapeutic modalities that directly target the signaling pathways constitutively activated by mutant TNFR1 is thus apparent.
These outcomes form an important element of the pathway to the final impacts column and demonstrate the importance of identifying all the links in the chain of reasoning.
