Sentence examples for importance of gene expression from inspiring English sources

Although the results of Dennis and colleagues [ 1] are scientifically important and demonstrate the importance of gene expression profiling in the search for predictive biomarkers, the individual patient-based ROC analyses show only modest predictive ability and therefore weak clinical utility.

The importance of gene expression changes in diversity is further highlighted by the observation of a lack of conservation in expression relationships among human and chimpanzee cortical genes [11].

This success demonstrates once again the decisive importance of gene expression data obtained after systematic gene perturbations and highlights the usefulness of graph analysis to increase the reliability of inference.

94 We note two additional points about the importance of gene expression for population persistence.

Recent transcriptome-wide analyses underscore the importance of gene expression in the genetic architecture of complex traits.

This underlies the importance of gene expression studies of response and the need to provide increasing benefit with administered treatments through the identification of robust peripheral biomarkers.

Nevertheless, increasing evidence supports the importance of gene-expression variability in regulating complex traits.

Furthermore, to demonstrate the importance of normalization of gene expression with appropriate reference genes, we tested the effect of using a combination of the least stable genes for expression analysis evaluation.

Since miRNAs can regulate more than one target, estimates indicate that they regulate up to 30 percent of the protein-coding genes in the human genome, highlighting their importance as regulators of gene expression.

In addition, as a first comprehensive gene expression profile of putative human epithelial cells isolated directly from tissue, the generated database may be of importance for studies of gene expression profiles of other human epithelial tissues.

In the present study Hnf4a (hepatocyte nuclear factor 4, alpha) was repeatedly implicated as being of potential importance for coordination of gene expression during the early stages of acclimation to zinc restriction.