These differences probably reflect sampling time relative to the onset of sepsis and emphasise the importance of not extrapolating data from sepsis biomarker studies performed in one setting to another.
This is the first study of FCD under stochasticity, the importance of which extrapolates to any cell signaling study.
This large longitudinal dataset reveals a dynamic picture of invasive Salmonella disease in Blantyre, which emphasizes the importance of country-level surveillance for severe BSI and the pitfalls of extrapolating data across African settings or between different time periods.
Mr. Bagemihl is also wary of extrapolating.
But we should be wary of extrapolating from history.
A drug identified in an in vitro study is not necessarily of clinical importance, and extrapolating from animal evidence to humans is not always simple.
This has great importance when extrapolating test results with relatively small numbers of samples (dozens at most) to the case of a modern processor that may have hundreds of thousands of potential failure sites (Lloyd et al. 2006).
The low sticking efficiency values measured express the importance of the long columns used in the experiments and the lower values of extrapolated minimum sticking efficiencies makes the method a valuable tool in delineating protection areas in real-world scenarios.
Recently, the risk assessment and atmospheric modeling communities have recognized the importance of developing approaches to extrapolate estimates from other studies in situations where input data are limited or comprehensive models are impractical.
To extrapolate the functional importance of this electrostatic interaction to mammalian nAChRs, we introduced the equivalent D197A and D195A mutations in α3β2 and α7 nAChRs, respectively, and compared the potency of TxIA analogs by two-electrode voltage clamp analysis on the oocyte expressed mutant receptors.
