In fact, α-syn propagation was more pronounced in the absence than in the presence of neurodegeneration, underscoring the importance of neuron-to-neuron α-syn transfer between intact, relatively healthy cells.
These examples highlight the importance of neurons and neuronal gene function in the regulation of lifespan.
The highly importance of the neuron for human brain stems form its ability to process and transmit information through electrical and chemical signals.
The high correlation between female preference and neuronal threshold values of the AN1-neuron (figure 2B) points to the importance of this neuron for mate choice decisions [19].
More recent studies using antimitoic and DNA alkylating agents, irradiation, targeted viral vector, and genetic approaches to more specifically disrupt neurogenesis provide further support for the importance of new neuron proliferation/maturation in learning and memory [29], [30], [31], [32].
Our comparative analysis of CREB1 expression during aging in the intact ganglia and individual neurons highlight the importance of single neuron study of aging.
Execution of such complicated tasks emphasizes the importance of corticospinal motor neuron (CSMN) health and stability for proper motor neuron circuitry.
Given the notion that unf promotes MB axonogenesis possibly through regulating neuron subtype identity, its selective involvement in late MB morphogenesis could simply reflect the importance of neuron subtype identity in ensuring diverse subtype-specific axonal morphogenesis.
Despite the importance of neuron electrical activity for influencing appetite and body weight, only a few ion channel subunits have been determined in these cell types and little is known about their regulation by energy deficit state.
Given the importance of LKB1 in neuron development and polarisation (Barnes et al., 2007; Sun et al., 2011), the absence of any evident neuronal phenotype in the present model was surprising.
