The importance of deleting alloreactive CD8+ T cells for allograft survival was further confirmed by the finding that adoptive transfer of pre-sensitized syngeneic CD8+, but not CD4+, T cells abrogated the long-term allograft survival in our model.
The importance of the deleted regions within each MA3 domain is unknown but the elucidation of their structural or functional impact on the MA3 domains will provide insight into the adaption of PDCD4 proteins in early evolved gymnosperm and angiosperm species.
deleted ← 0 {deleted denotes the number of deleted beats}.
c Number of deleted (del).
Move files instead of deleting.
We have analyzed the importance of N-Spc98 by deleting different portions of this domain including the helices, the linker region, and both the helices and the linker.
The importance of short direct repeats flanking deleted DNA was first shown as a RecA-responsive process in bacteria (Albertini et al. 1982).
To assess the relative importance of DNA repair systems, recA was deleted.
To determine the importance of this putative UBL element, we deleted the region encompassing the UBL motif (amino acids 250 350; UBLΔ also termed as d2Δ in Figures 3 and 4) at the genomic USA1 locus.
Using the placental-specific IGF-II-knockout mouse (P0), in which a placental-specific promoter of IGF-II has been deleted, the additional importance of placentally derived IGF-II on placenta and fetal weight has been verified (10).
