This underscores the importance of CF testing in patients with persistent, refractory CRS who do not exhibit classic pulmonary or gastrointestinal CF manifestations.
The Toccata clinical trial using the TactiCath™ catheter (St Jude Medical GVA, Geneva, Switzerland) was the first study to demonstrate the importance of CF sensing for improved clinical outcome.
This study provides a number of unique insights that confirm the critical importance of CF for the electrophysiologist: Dormant conduction identification and elimination has been shown to improve long-term clinical results after PVI.
The absence of pathogenicity and the ability to produce great amounts of a stable xylanase active in both acidic and alkaline pH, with highest specific activity in 72 h of incubation, emphasize the importance of A. cf. tubingensis LAMAI 31 as a marine genetic resource for biotechnological applications.
If we want to consider the order of importance of the biomarkers (cf. Tables S4 and S5), we consult their VIP in the corresponding minimal variable selections, which is in general slightly different from the VIP in the original PLS-model that included all measured predictor variables.
Today, the importance of an appropriate CF during left-ventricle (LV) mapping and ablation is widely accepted.
However, plasma FA largely represented a transport pool rather than a functional pool, which therefore underscores the importance of studying FA composition of CF-affected tissues and cells.
Recent reports have emphasized the importance of studying the presence of cf-DNA and the possible association with various diseases.
The importance of this colonization in CF patients is still unclear.
As with most neuropsychiatric disorders, there are no characteristic neuropathological findings (Table 1), which, coupled with the absence of any diagnostic tests and substantial clinical heterogeneity (variable signs and symptoms), emphasizes the importance of detailed expert phenotyping (cf "shallow phenotyping").
