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The importance of cAMP as a negative regulator of phagocyte function is further indicated by the fact that several pathogenic microorganisms elevate cAMP in target host cells [5].
Taken together, these results establish a direct link between Foxp3 and miR-155 in human T cells and highlight the importance of cAMP in the miR-155 induction cascade elicited by H. pylori infection.
A case in point for the importance of cAMP signaling in flagella is the mammalian sperm cell.
The importance of cAMP signaling for H. jecorina is highlighted by the finding of 5 putative cAMP-GPCRs.
To further evaluate the potential importance of cAMP phosphodiesterase for increasing cAMP production, we reexamined the effect of PDEs knockdowns in the synthetic lethality screen.
However, all of these studies were all focused on assessing the importance of cAMP in leukaemogenesis, as they were undertaken when the property of forskolin as PP2A activator was still unknown.
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Given the importance of the cAMP pathway in dopamine signaling [24], [25], we decided to elevate cAMP levels directly in hippocampal neurons by treating cultures with 3-isobutyl-1-methylxanthine (IBMX, 100 µM).
During his life, he frequently wrote about the importance of the camp meeting in bringing Christianity and democracy to the west.
The present results in left cardiac ventricles of control rats are consistent with those data, and they highlight the importance of cardiac cAMP catabolism in regulating cardiac contractility.
Gene expression during adaptation to new environmental conditions like a high salt concentration has been determined in A. platensis, and the importance of the cAMP signalling cascade in its regulatory mechanism in response to changes in the external environment has been highlighted.
Realizing the importance of the cAMP-PKA-dependent pathway in regulating the angiogenic network, we questioned whether it contributes to impaired angiogenesis during the course of diabetes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com