Sentence examples for importance of binding from inspiring English sources

It is hard to define a threshold for the functional importance of binding sites under this concept, and it makes the problem of selecting the complete set of important binding sites more vague.

We quantify the functional importance of binding sites by calculating their impact on gene expression in the model and calculate how these impacts correlate across all sites under different modeling assumptions.

All eight of those PWM families represent homeobox transcription factors (Table 1); their enrichment and conservation likely reflect the importance of binding sites for homeodomain proteins Lhx2 and Emx2 (represented by matrices in the V$LHXF and V$HBOX families, respectively) in OR promoters [ 28- 30].

This study suggests the importance of binding of anticancer drug to AAG spatially in the diseases like cancers where the plasma concentration of AAG increases many folds.

A decade ago, the drug-target residence time model has been (re- introduced, which descre- introducedrtance of binding kinetics of ligands on their protein targets.

These findings underline the importance of binding loop rigidity in canonical serine protease inhibitors and the need to maintain structural stability when modifying compounds of this class.

Function-blocking experiments clarified the functional importance of A11-binding sites on chaperones (Figure 5).

To evaluate the synthesized chemical library, researchers need to consider high-throughput affinity assays, the analysis of specific binding, and the importance of fast binding kinetics.

Interestingly, inactivation of wt p53 often occurs as single point mutation in the core DNA binding domain, suggesting the importance of DNA binding for the tumor suppressor function of wt p53.

The importance of the binding surface selection is highlighted; a binding path with no cavity and made up of all hydrophilic residues was shown to be not very suitable for determination of a candidate binder peptide.

Con A is a carbohydrate-binding protein; the literature indicates the importance of carbohydrate binding in various biological processes.