Sentence examples for importance of bid from inspiring English sources

Importance of BID for apoptosis has been reported for several cancer cell lines that became either more sensitive to apoptosis after expression of BID or more resistant to it after silencing expression of the protein [ 8– 11].

Given these special characteristics of Bid compared to other BH3-only proteins, we established a stable knockdown of Bid expression by a gene silencing approach in HeLa cervical carcinoma cells and addressed the functional importance of Bid expression in death receptor- and stress-induced apoptosis in a human cancer cell line.

In mice, Scatizzi and colleagues recently showed the importance of Bid for arthritis [ 23].

To determine the importance of Bid in TRAIL-induced death, H357 and HSC3 Bid knockdown and control cells were generated and analysed for response to TRAIL.

These studies indicate the importance of Bid cleavage by caspase-8 as the initial step in the protein degradation, and the protection from caspase cleavage could be expected to prevent Bid degradation.

To investigate the importance of Bid or Bim in the regulation of sensitivity and resistance towards apoptosis induction in HTLV-1-infected T cells, we transiently transfected expression plasmids containing either Bid or Bim cDNA into the HTLV-1-infected T-cell lines MT-2 and Hut-102.

Given the growing importance of bit.ly, it would not be surprising to see a heated bidding war between Facebook, Twitter, Google and Microsoft.

The importance of simulating bidding strategies of electricity markets can be investigated from several points.

To further confirm the importance of Bim and Bid in paracetamol plus TRAIL-mediated cell death, we isolated LSECs from Bim−/− and Bid−/− mice. Figure 6 shows that Bim−/− as well as Bid−/− LSECs display attenuated induction of cell death after paracetamol plus TRAIL stimulation compared to wild-type LSECs.

To further confirm the importance of Bim and Bid in the contribution of apoptosis sensitivity, we carried out an siRNA approach to knockdown Bim and Bid in the non-HTLV-1-infected T-cell line Jurkat.

Senior officials expressed frustration that it came after Israeli officials had played down the importance of the Palestinian bid and suggested that they would only employ harsh retaliatory measures if the Palestinians used their new status to go after Israel in the International Criminal Court.