Sentence examples for importance of activation of from inspiring English sources
Our study also supports the importance of activation of endogenous retrotransposons as an important, and probably universal, feature of cancer.
Here, we mainly focus on pathway engineering of two sp3 carbon-rich bioactive indole alkaloids, fumitremorgin C and terpendole E. We also demonstrate the importance of activation of secondary metabolism by focusing on tenuazonic acid, a bioactive tetramic acid compound, as an example.
SRC family kinases, LYN and LCK, were abundantly phosphorylated on their activation sites in these AML samples, consistent with the importance of activation of SRC family kinases in AML survival [43].
Further studies are required to determine the clinical importance of activation of the EGF-R signalling pathways and the downstream effect on VEGF and NRP-1 expression.
The importance of activation of both types of signalling in sensitisation of cancer cells to TRAIL has been recently shown for prostate cancer cells (Ray and Almasan, 2003).
Clinical approaches for LPP management have specified the importance of activation of muscles for motor control and stability of the lumbopelvic region [ 39] and physical exercise has been indicated as a beneficial method to relieve LPP during pregnancy and after child birth [ 22, 40– 40].
The importance of activation or repression of cap-mediated translation in mesothelioma is strongly emphasised by the observation that an enforced repression of translation in mesothelioma cells resulted in the near total loss of tumourigenic potential.
The revised DSM-V criteria recognize the importance of activation as a cardinal feature of bipolarity, which is often a manifestation of underlying circadian rhythm dysregulation [ 40, 41].
The importance of activation is supported by the lack of a phenotype in transgenic mice that overexpress LTGF-β in mammary gland [ 11].
To our knowledge, all cells secrete LTGF-β, which underscores the importance of activation events associated with the release of TGF-β from LAP. TGF-β message levels do not usually reflect protein production, or, more importantly, protein activity.
The identity and quantity of bacteria in the fetal membranes is likely to be of importance as activation of the innate immune pathway in chorion and decidua is thought to be a key event in the aetiology of preterm birth [16], [17].
