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Extending the scope of Suzuki coupling reaction in regioselective domain a series of 2,5-dibromo-3-methylthiophene derivatives has been synthesized specially with aim to explore their biological importance for the first time.
This year's local elections, usually fought on important local issues from rubbish collection to fly tipping, have been gifted a unique importance: for the first time in 30 years, a local election campaign precedes a general election in the same year.
We performed a GWAS and candidate gene study investigating a variety of smoking behaviors with public health importance for the first time in a sample unselected for smoking behaviors and/or smoking attributable disease.
Therefore, antiviral therapy for influenza A viruses including highly pathogenic H5N1 virus strains remains of great importance for the first line defense against the virus [1] [4], [6], [9].
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The inhibition of enzymes by the enzymatic product or by an unsuitable substrate is known to be a key problem in biofuel production [ 1, 22- 25] and the characterization of the mechanism of inhibition is of fundamental importance for the second-generation biofuel industry.
Based on the responses to the round 1 questionnaire, we categorised the criteria into high (70% or more respondents ranked criteria as 6 or 7 on the scale of importance), intermediate (50-69% ranked criteria as 6 or 7 on the scale of importance) and moderate priorities (less than 50% ranked criteria as 6 or 7 on the scale of importance) for the second round questionnaire.
This highlights the crucial importance of the first postnatal hours for establishing mother-infant interaction.
In the 1970's PBPK/PT models were developed to evaluate metabolism of volatile compounds of occupational importance, and, for the first time, dose-dependent processes in toxicology were included in PBPK models in order to assess the conditions under which saturation of metabolic and elimination processes lead to non-linear dose response relationships.
His initial wish to protect his home turns into a gruesome right-wing advert for the importance of the second amendment and a pre-pubescent spin on Falling Down.
And it was in the Beijing Declaration that the importance of women's economic importance was recognized for the first time: a full third of the framework's recommendations dealt with women's economic participation.
Van Heugten, who has been researching this period of the artist's life, says his time in the Borinage was of huge importance, bringing him for the first time into contact with true poverty and the hard lives of working-class people.
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