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These data imply functions in virulence-coupled autolysis for SAR2421 (lyrA), SAR1223 (lytN) and SAR1802 (hypothetical).
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The best, made around 1935, depict tabletop arrangements of organic forms (recalling Arp and Miró) that resist recognition, but imply function; one biomorphic blip sports a circle inscribed with a dash that looks uncannily like the head of a screw.
Any omissions imply function defaults.
Why then does binding not necessarily imply function?
This is consistent with a previous finding that physical interactions imply function in a single pathway and are orthogonal to synthetic lethal interactions [ 27, 28].
A separate collection of unfertilized eggs was taken to determine the maternal contribution to transcript abundance of selected CYP genes, which could imply function in early development.
Further functional experimental studies will be needed in order to fully verify these as real ncRNAs since transcription does not imply function.
Yet, in vivo and in vitro, binding of transcriptional control (TC) proteins to their cognate DNA response elements (REs) or of protein molecules to their protein partners does not imply function.
We established transcription for several of the nuwts examined, however transcription does not necessarily imply function [ 5] and it appears that low-level transcription is common among nuwts [ 4, 11- 13].
We only interrogated a limited shRNA library focused genes with implied functions in proteostasis.
That this shared domain architecture implies functions in common, has now been demonstrated experimentally [ 34, 35].
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