This implies that the uncertainty of the estimated intrinsic half-lives is less than a factor of 1.5.
Since all predictions of state 3 start with an initial condition of zero, this implies that the uncertainty at this point is low.
(Furthermore, ignoring the treatment effects in terms of shape, i.e. assuming a constant HR, implies that the uncertainty in model shape is not captured with the meta-analysis models).
In the latter case, uncertainty implies the firms' limited knowledge of external changes, such as those in regulations and the market (e.g., consumption and competition).
According to this argument, higher environmental uncertainty implies the presence of more cooperation in surviving populations, which is in good agreement with our simulation findings.
And in fact, I have found this to be the case in my empirical study of polls; less volatility in the polls implies less uncertainty about the eventual outcome.
We need to consider that published P o data for the Ca 2+ conductance associated with the TPC2 signaling complex, on which we based our TPC2 rate table, show some variability according to the standard deviation bars, which, in turn, implies an uncertainty in the interpolated P o.
The literature in this field appears to be relatively sparse and implies considerable uncertainty regarding the input parameters of our decision analytic model.
The fact that the questionnaires were filled out by individual practitioners in their everyday environment and not by calibrated investigators in an optimal research facility explains that the response rate to each question was not 100% and also implies some uncertainty as to the validity of the answers, especially those that included an element of estimation, e.g., of post diameter.
Probabilistic sensitivity analysis demonstrated an incremental NHB of ABI if rehabilitation fails compared to cardiac rehabilitation only of 0.03 QALYs (95% CI: −0.17, 0.29), which implies considerable uncertainty around the outcome.
"One of the lessons from the Great Financial Crisis is that large changes in prices and exchange rates, and the implied increased uncertainty about the position of some firms and some countries, can lead to increases in global risk aversion, with major implications for repricing of risk and for shifts in capital flows.
