He added: "This would imply altering early next year the size, pace and composition of our measures".
These results implying altered trigeminal excitability of the trigeminal system of MM in both headache and headache-free period and the brainstem excitability of MM patients was found to be different from that of normal subjects.
The present results imply altered cortical reactivity of the primary somatosensory cortex in FMS patients and MB possibly reflecting differences of individual pain experience.
All in all, the present results imply altered cortical reactivity of the primary somatosensory cortex in FMS patients and subjects with masochistic behaviour suggesting that individual pain experience affects tactile processing in S1.
These data imply altered signaling events associated with 5-HT7.
Overall, these data indicate that the positive effect of AMPK on Nrf2-mediated transcription in our system does not imply altered abundance or nuclear translocation of Nrf2.
Further effects imply altered insulin signaling, reduced availability of nitric oxide, and mitochondrial damage that can lead to abnormal cardiac structural and functional remodeling [ 26, 39].
In the current investigation, the cortisol increment was significantly lower in the bacteremic group, implying altered adrenal synthesis and responsiveness in this specific subset of patients.
The short variant of the protein, Lyp2 (corresponding to PTPN22_v4), lacks the consensus motif for CDK1, implying altered cell cycle-related regulation of this transcript in lymphoid cells compared to Lyp1 [ 3].
Finally, higher abundance of transcripts for genes involved in innate cellular immunity and lower abundance of transcripts for humoral immune components implied altered immune competence in response to elevated temperature.
