Sentence examples for implied in the pathogenesis from inspiring English sources

Although there are clear diagnostic differences in the primary pathology of both diseases, i.e., death of dopamine-generating cells in the substantia nigra in PD and neuroinflammation in HIV, neurotoxicity to dopaminergic terminals in the basal ganglia (BG) has been implied in the pathogenesis of HIV and neuroinflammation in the pathogenesis of PD.

It is implied in the pathogenesis of lysosomal storage disease and osteopetrosis.

Several signaling mechanisms beyond cell surface receptors, which are activated by adrenergic signaling and other neuroendocrine compensatory systems, have been implied in the pathogenesis of chronic heart failure.

Deregulation of COX-2 has been implied in the pathogenesis of several cancers, in particular colorectal cancer, where it impacts on oncogenic signaling, invasion and metastasis, survival and angiogenesis.

The dimensions of the cervical intervertebral foramina may change during neck movements and could be implied in the pathogenesis of diseases associated with cervical radiculopathy such as CSM and intervertebral disc disease.

Cell contact of monocytes with preactivated T cells is one of the strongest known stimuli of monocytic cytokine production and has been implied in the pathogenesis of rheumatoid arthritis (RA).

Intriguingly, CCL22 has been implied in the HIV pathogenesis in several ways.

Several IL-15 signalling pathways are also implied in the putative pathogenesis of systemic sclerosis (SSc).

Exposure to excessive 4-HNE can cause cytotoxicity, inactivation of enzymes, redox imbalance and activation of multiple signaling events, and 4-HNE is implied in the detrimental pathogenesis of a number of degenerative diseases including cancer [ 5, 6].

Angiosperm Class II formins usually (though not always) carry a N-terminal domain related to members of another conserved protein family whose founding member is the human antioncogene PTEN, recently implied also in the pathogenesis of the Parkinson disease (reviewed in [ 17]).

Deregulation of the MAPK genes signalling caused by somatic mutations have been implied in leukaemia pathogenesis, including RAS mutation (RASmut) in acute myeloid leukaemia (AML), which has been associated with intra-uterine chemical exposures.