We demonstrated that the risk variant is associated with enhanced astroglial NF-κB signaling and upregulation of a subset of NF-κB target genes that drive lymphocyte recruitment and neurotoxicity, as implied by increased expression of C38.
Maurice Obstfeld and Alan Taylor calculated hypothetical profits as implied by the expression of a potential inequality in the CIRP equation (meaning a difference in returns on domestic versus foreign assets) during the 1960s and 1970s, which would have constituted arbitrage opportunities if not for the prevalence of capital controls.
The disparity between these in vitro and in vivo findings could then reflect differences in the homing potential of the three tested MSCs types, as implied by differential expression of integrin-α4 and the inability of integrin-α4-negative BM-MSCs to traffic to the CNS [ 70].
Furthermore the apparent partial dependence of skin-specific Irga6 expression on IFN action implied by the reduced expression in IFN receptor-deficient mice may suggest that Irga6 expression in the skin is not primarily constitutive but rather due to continuous low-level stimulation of immunity in this barrier site.
Activation of WNT signalling is further implied by an evident expression of β-catenin within the nucleus rather than in cytoplasm or membrane in tumour-budding cells, as well as increased laminin 5 gamma 2 and activation of SLUG and ZEB1(Muto et al, 2006; Schmalhofer et al, 2009).
A potential role of JNK in miRNA regulation is implied by an altered miRNA expression in JNK-deficient cells and by an altered binding pattern of certain miRNAs in Ago2/JNK complexes upon JNK phosphorylation.
This is implied by their more prominent expression at the earlier embryonic and larval stages and their loci being enriched in Polycomb protein associated domains which are known to harbor developmentally relevant genes.
The occurrence of MLG in lichens [ 51], fungi [ 52], green algae (Micrasterias) [ 13], horsetails [ 53], and Poales [ 54] has been suggested to result from convergent evolution [ 55], whereas the occurrence of distinct MdEXPs might be connected to two different (primary and secondary) cell wall types, implied by their different temporal expression patterns.
This conclusion is supported by analyses that involve fitting weighting expressions implied by the Armitage Doll model.
Because the Communist-influenced Broadway script emphasizes the wrongs implied by universal, rather than specific, expressions of tyranny, James's philosophy anticipates, and perhaps even helps frame, Levin's still-pertinent charge that generalization abets both Holocaust denial and efforts to disavow Jewish identity, particularism, and nationalism.
