A key aim of logic models is to uncover assumptions in the chain of reasoning between interventions and their expected impacts, and to develop a theory of change which sets out these implicit "if…then" pathways.
Although many uveal melanoma samples have been studied for BRAF and NRAS mutations, few have been analysed for MAPK activation and there is the implicit assumption that this pathway is not involved in uveal melanoma genesis.
The residues associated with the major pathway found by implicit ligand sampling are highlighted in Figure 1b.
Tanya K. Hernandez, is a Professor of Law at Fordham University School of Law, where she teaches Anti-Discrimination Law, Comparative Employment Discrimination, Critical Race Theory, The Science of Implicit Bias and the Law: New Pathways to Social Justice, and Trusts & Wills.
Cohen and Schulten used implicit ligand sampling to demonstrate different pathways in a variety of globins.
Thus, besides the glucose-dependent uptake of glucose by the liver, other pathways of glucose disposal are implicit in the forcing-function construct.
Taken together, these results indicate that implicit information about the connectivity between signal transduction pathways and transcription factors can be obtained by comparing the activity profiles of TFs.
Thus, the CaMKII signaling pathway is critical for both explicit and implicit memory storage, in a manner that is independent of its potential role in development.
Previous studies have used implicit ligand sampling (ILS) to identify the potential escape pathway between the B and G helices.
Little attention is usually paid to the conservation of secondary targets, such as proteins in the pathway downstream of the primary target, which is an implicit requirement for the read-across hypothesis to be fully valid.
