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We discuss the implications of viral infiltration of this pathway for both the transcriptional program of the virus and for the cellular response to DNA damage.
Here we review the implications of viral kinetic models at the different stages of development of anti-HCV agents.
Standard population genetics has no model for such a variable-ploidy organism, and only a handful of authors have considered the theoretical implications of viral coinfection in detail [ 67- 81].
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However, the implication of viral shedding pattern and cDNA viral load on epidemiologic characteristics and clinical manifestations of NoVs deserves further investigation.
To investigate the implication of viral infection in OA, we analyzed cartilage and chondrocytes obtained from advanced OA and non- or early OA patients for signs of active viral infection.
Despite the two previously cited papers demonstrating increased radiosensitivity of HPV/p16-positive cells [ 34, 35], there is no clear evidence for the implication of viral oncoproteins in radioresponse, and data published so far are inconclusive or even sometimes conflicting.
The implication of viral DNA integration into host cells on drug sensitivity is not known, although in vitro data suggested that expression of hepatitis B viral proteins may increase apoptosis threshold and resistance to cytotoxic agents of cancer cells (Doong et al, 1998; Shih et al, 2000).
Among the potential environmental factors, epidemiological, clinical, and pathological studies in humans support the implication of viral infections, particularly enteroviruses (e.g., coxsackievirus; CVB), as triggers for the development of T1D (Helfand et al., 1995; Dotta et al., 2007; Yeung et al., 2011; Morgan and Richardson, 2014; Richardson et al., 2014).
In addition, we demonstrated that the potential implications of enhanced viral polymerase activity to human health.
This is an important conclusion in terms of the medical implications of oncolytic viral therapy.
There is no consensus in the literature on the clinical implications of the viral detection and co-detection.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com