Sentence examples for implications of this mutation from inspiring English sources

Exact(3)

The biological implications of this mutation remain to be investigated.

We have deliberately not drawn implications of this mutation to clinical resistance.

The reader is directed to some comprehensive surveys of the studies so far that point to some possible implications of this mutation in a variety of diseases (e.g., cancer, cardiovascular disease).

Similar(57)

By extensively analyzing the sequence of CD20 molecules of various monkeys and primates, we should be able to obtain insight into the evolutional implication of this mutation.

As a matter of fact, the patient failed to respond to the TKI therapy, although functional studies are necessary to better clarify the patho-physiological implications of this particular mutation.

Finally, we discuss the potential functional implications of the mutation and suggest future prospects to evaluate the effect of the mutated CEP63 on cellular functions.

They reported mtDNA mutations in nine tumoral mtDNAs (one mutation per patient) and, in particular, inferred pathogenic implications of the mutation A15296G in leukemia.

Analysis of the structural implications of the mutation (Fig.  7C, 1 and 2) would suggest a possible disruption of the C-terminal helix α20, resulting in a change of the secondary structure that would favour ACE shedding from its membrane-bound anchor.

The implications of these mutations are discussed using a structural model of the XPD protein.

To study the structural and functional implications of these mutations on RING2-REP domain of Parkin, we studied the solvent accessibility (SASA/RSA), hydrophobicity, intra-molecular hydrogen bonding profile and domain analysis by various computational tools.

Further investigation is warranted as to the functional implications of these mutations in carcinogenesis.

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