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RNA viruses are notorious for rapidly generating genetically diverse populations during a single replication cycle, and the implications of this mutant population, often referred to as quasispecies, can be vast.
In addition, we have also performed a more complete analysis of the substrate concentration dependence of the 5D mutant of 4p-PTEN lipid phosphatase activity, and these results fortify the interpretation of the regulatory implications of this mutant.
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SS: And they're clearly unfazed by the ethical implications of consuming this mutant dish.
In order to assess the long term implications of this, the mutant and parental strain were subjected to starvation survival experiments over a period of 3 weeks (Fig. 2B).
The fact that the deletion of pppA-ppkA genes influenced stress tolerance and substantially decreased intracellular survival in the murine macrophages raised the possibility that it could also have significant implications in the ability of this mutant to cause disease.
These findings have implications in the potential use of this mutant class in agronomy as well as in designing genetic screens for drought tolerance.
We concur that the implications of SPOP mutant cancers as a target for PARP inhibition is potentially important.
We show the initial crystallographic structure analysis of this mutant and its preliminary implications.
We contrast these results with those found previously for the AtTOR mutant, and discuss the implications of this work for TOR signaling in plants.
The emergence of this mutant strain of a sexually transmitted pathogen has implications for public health practice.
Understanding the underlying implications of mutant TET2 lacking function and its role in myeloid malignancies is a current research priority.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com